Conformation of cyclic dipeptides.Ab initiocalculations on cyclo (glycyl-glycyl), cyclo (D-alanyl-L-alanyl), and cyclo (L-alanyl-L-alanyl)
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چکیده
منابع مشابه
Crystal structure of the dipeptide cyclo(glycyl-l-glutamine).
that produces opioid-like effects on the central nervous system.1 Cleavage of the β-endorphin C-terminal in the brain and pituitary gland yields the biologically active dipeptide glycyl-Lglutamine (Gly-L-Gln, β-endorphin 30-31), which inhibits βendorphin-induced cardiorespiratory depression.2,3 The stereospecificity of this effect is evident, since Gly-D-Gln has recently been reported to be ina...
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Glycyland alanyl-tRNA synthetases have been purified from an extract of Bombyx mori posterior silk glands by a procedure that allows for the simultaneous isolation of both enzymes. Glycyl-tRNA synthetase is a dimer of M, = 160,000 consisting of similar or identical subunits, whereas alanyl-tRNA synthetase is a monomer of M, = 110,000 to 116,000. The abundance of these two enzymes in the posteri...
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We described elsewhere that the synergistic antitumor activity of endotoxic extracts from Re mutants of gram-negative bacteria and trehalose mycolate against guinea pig syngeneic line 10 tumor was abrogated after peptide substances accompanying these extracts had been removed. This activity could be restored by combining peptide-free endotoxin either with cell wall skeleton from Bacillus Calmet...
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BACKGROUND Ischemia/reperfusion injury during liver transplantation can cause severe damage to the graft. The objective of this randomized, double-blind study was to evaluate the possible protective effects of L-alanyl-glutamine on the liver graft. METHODS The sample included 33 patients from a liver transplantation service in Northeastern Brazil. Before cold ischemia, the patients received 5...
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ژورنال
عنوان ژورنال: Biopolymers
سال: 1976
ISSN: 0006-3525
DOI: 10.1002/bip.1976.360151117